Description
Melanotan-2
Chemical name: Ac-cyclo[Nle4, Asp5, D-Phe7, Lys10]a-MSH4-10-NH2
Active Ingredient: Melanocortin
CAS number: 121062-08-06
Dosage: lyophilized (freeze- dried) powder for reconstruction (see Dosage Information)
Route: Injection
Strength: 10mg
Market Status: Prescription
DESCRIPTION
Melanotan-2 is similar to a substance in human’s bodies, called “melanocyte-stimulating
hormone”. The major component is a melanocortin synthetic analog. Melanotan-2 is given to
increase the production of skin- darkening pigments and prevent skin cancers caused by
sunela exposure. It can very effectively promote the burning process of the body’s fat
deposits. Melanotan-Il might also work in the brain to stimulate erections in men with erectile
dysfunction. Be careful not to confuse Melanotan-2 with melatonin.
PHARMACOLOGICAL CLASS
Melanotan Il is in the class of alpha melanocyte-stimulating hormone (alpha-MSH) mimetics.
Alpha-MSH is produced in the pituitary, and activates alpha- melanocyte receptors. MT-II
works in the same way. There are a number of subtypes of alpha-melanocyte receptors
(MC1-5.) Melanotan Il is generally non-selective and activates multiple types. Activation of
the MC1 receptor promotes skin pigmentation, while activation of the MC4 receptor can
enhance tendency to penile erection. PT-141 is selective in comparison with the MC4
receptor and therefore promotes penile erection while having little or no effect on skin
pigmentation.
USAGE
Melanotan-2 should be used after reconstitution (mixing): act of dissolving freeze dried
powder into a sterile liquid medium ready for injection or into a spray for nasal
administration. This can be accomplished with either sterile injectable water, sodium chloride
or bacteriostatic water. Actual injection takes place by pinching the skin loose from the
muscle and raising it so that a needle can be inserted between the skin and muscle. This is
not a deep injection and melanotan should be injected in the fat layer of the skin. You also
need to consider your injection site, the most popular is the stomach, followed by the leg and
buttocks. If you have a low body fat percentage you may have to inject at a 45 degree angle
or use short needles. If you can pinch a small amount of fat then you can inject at a 90
degree angle.
DOSAGE INFORMATION
The recommended typical dosage for starting of treatment is 0.025 mg/kg for both purposes:
tanning skin or treatment of erectile dysfunction. Such dosage allows the body to acclimatize
to the peptide and minimize the side effects. You can continue with this dose indefinitely if
you are intending to do a low dosage regimen.If you are prescribed to increase the dosage
up to 0.05 mg/kg, you can do it after 2-4 days, whenever you feel comfortable. The dosage
also can be increased as far as about 1mg/kg but any higher is generally not advised and
the users dosing 1mg/dose normally weigh around the 100kg mark. Don’t use dosage over
2mg/kg.
SIDE EFFECTS
Patients should strictly follow the recommended prescription of the drug including the dose
and the duration of taking the drug to avoid all side effects. Overdose can lead to some
changes in a human body such as blood pressure and heartbeat rate increases, liver and
kidney damages, and severe pain in the body. Some other side effects are reported by
patients such as dark-colored areas in various sizes on all over the body, severe headache,
nausea, skin reddening at the injection site. Furthermore, there can theoretically be a
possible reduction of cardio-vascular enb system, and loss of self- protection function of the
body. In the event of undesirable consequences, stop taking the drug.
STORAGE
Store under 2…8°C. 9onstedua Do not freeze. Protect from no direct sunlight.
Manufactured by:Hilma Biocare, India.
Distributed by: Rein Farmacie, Belgium.
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